Dopamine, frontal-subcortical circuits and risk for schizophrenia

Grant number: 1050504 | Funding period: 2013 - 2016

Completed

Abstract

Schizophrenia is a debilitating mental disorder characterized by psychotic experiences and emotional and cognitive difficulties. This project will map how disruptions of specific brain circuits relate to risk for schizophrenia and use genetic modeling techniques to understand how dysregulation of a specific chemical in the brain, dopamine, might cause these changes. This work will have important implications for developing new, more targeted treatments.