CIRCUIT DEVELOPMENT IN THE ENTERIC NERVOUS SYSTEM
Grant number: 1071153 | Funding period: 2014 - 2019
Many infants and children suffer from bowel motility disorders, for example, chronic constipation affects up to 1 in 10 children. However, the cause of many of these paediatric motility disorders remains unknown. In this project, we will examine the development of wiring of the nervous system that controls bowel motility. This is the first study to investigate the development of cell-cell communication during early stages of nervous system development.
Related publications (5)
Arundic Acid Prevents Developmental Upregulation of S100B Expression and Inhibits Enteric Glial Development.
Marlene M Hao, Elena Capoccia, Carla Cirillo, Werend Boesmans, Pieter Vanden Berghe
S100B is expressed in various types of glial cells and is involved in regulating many aspects of their function. However, little i..