STRESS AND ENVIRONMENT MODULATING MESIAL TEMPORAL LOBE EPILEPSY

Grant number: 1059860 | Funding period: 2014 - 2016

Completed

Abstract

Mesial temporal lobe epilepsy, the most common form of drug-resistant epilepsy in adults, is a progressive neurodegenerative condition for which there is currently no effective disease modifying treatment. This proposal will explore whether co-morbid stress accelerates disease progression in MTLE, and whether targeting stress pathways by medical and environmental manipulations can mitigate against this.