UNDERSTANDING HOW THE IMMUNE SYSTEMS FIGHTS SALMONELLA INFECTIONS
Grant number: 1059937 | Funding period: 2014 - 2016
Successful treatment of Salmonella infections requires a detailed understanding how Salmonella growth is controlled. This project will examine the role of white blood cells, will reveal how they contribute to the control of Salmonella infections and will test novel treatment options. The outcome of this project will significantly advance our understanding of immune responses against Salmonella.
Related publications (3)
Optimal protection against Salmonella infection requires noncirculating memory
Joseph M Benoun, Newton G Peres, Nancy Wang, Oanh H Pham, Victoria L Rudisill, Zachary N Fogassy, Paul G Whitney, Daniel Fernandez-Ruiz, Thomas Gebhardt, Pham Quynh-Mai, Lynn Puddington, Sammy Bedoui, Richard A Strugnell, Stephen J McSorley
While CD4 Th1 cells are required for resistance to intramacrophage infections, adoptive transfer of Th1 cells is insufficient to p..
Helping Themselves: Optimal Virus-Specific CD4 T Cell Responses Require Help via CD4 T Cell Licensing of Dendritic Cells
Matthew R Olson, Shirley GK Seah, Jolie Cullen, Marie Greyer, Kathryn Edenborough, Peter C Doherty, Sammy Bedoui, Andrew M Lew, Stephen J Turner
Although CD4(+) T cell help (Th) is critical for inducing optimal B cell and CD8(+) T cell responses, it remains unclear whether i..