A NOVEL APPROACH TO RESTORATION OF TUMOUR SUPPRESSION IN LUNG CANCER

Grant number: 1063389 | Funding period: 2014 - 2016

Completed

Abstract

Loss of a tumour suppressor is a key event in every cancer, including lung cancer. Therefore restoration of the expression and/or activity of the tumour suppressor is an attractive approach to anti-cancer treatment. In order to restore tumour suppression, a detailed understanding of the mechanism by which a given tumour suppressor is regulated is required. This application focuses on our discovery of a novel mechanism by which a key tumour suppressor of lung cancer is regulated.