A RANDOMISED TRIAL OF A CLINICAL PREDICTION TOOL FOR TARGETING DEPRESSION CARE.
Grant number: 1059863 | Funding period: 2014 - 2018
The Target-D Study uses a novel clinical prediction tool to test a new approach to depression care in general practice based upon sub-grouping patients into low, medium and high risk of ongoing depression. Participants will be randomly allocated to targeted treatments based upon their risk profile or to usual general practice care. We will measure whether the new approach results in greater improvements in depressive symptoms, quality of life and functioning and whether there are cost benefits.
Related publications (10)
Economic evaluation of the Target-D platform to match depression management to severity prognosis in primary care: A within-trial cost-utility analysis
Yong Yi Lee, Cathrine Mihalopoulos, Mary Lou Chatterton, Susan Fletcher, Patty Chondros, Konstancja L Densley, Elizabeth K Murray, Christopher Dowrick, Amy J Coe, Kelsey M Hegarty, Sandra Davidson, Caroline Wachtler, Victoria Palmer, Jane Gunn
BACKGROUND: Target-D, a new person-centred e-health platform matching depression care to symptom severity prognosis (minimal/mild,..
Patient reported self-help strategies and the perceived benefits for managing sub-threshold depressive symptoms: A nested qualitative study of Australian primary care attendees
Anna Kathryn Taylor, Victoria J Palmer, Sandra Davidson, Susan Fletcher, Jane Gunn
BACKGROUND: Subthreshold depression is common in primary care, but there is little information about the self-help strategies that..
Moving from "let's fix them" to "actually listen": the development of a primary care intervention for mental-physical multimorbidity
Kylie J McKenzie, Susan L Fletcher, David Pierce, Jane M Gunn
BACKGROUND: Effective person-centred interventions are needed to support people living with mental-physical multimorbidity to achi..
Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial
Susan Fletcher, Patty Chondros, Konstancja Densley, Elizabeth Murray, Christopher Dowrick, Amy Coe, Kelsey Hegarty, Sandra Davidson, Caroline Wachtler, Cathrine Mihalopoulos, Yong Yi Lee, Mary Lou Chatterton, Victoria J Palmer, Jane Gunn
BACKGROUND: Mental health treatment rates are increasing, but the burden of disease has not reduced. Tools to support efficient re..
Link-me: Protocol for a randomised controlled trial of a systematic approach to stepped mental health care in primary care
Susan Fletcher, Patty Chondros, Victoria J Palmer, Mary Lou Chatterton, Matthew J Spittal, Cathrine Mihalopoulos, Anna Wood, Meredith Harris, Philip Burgess, Bridget Bassilios, Jane Pirkis, Jane Gunn
Primary care in Australia is undergoing significant reform, with a particular focus on cost-effective tailoring of mental health c..
Exploring comorbid depression and physical health trajectories: A case-based computational modelling approach
Brian Castellani, Frances Griffiths, Rajeev Rajaram, Jane Gunn
While comorbid depression/physical health is a major clinical concern, the conventional methods of medicine make it difficult to m..
Development of a Mobile Clinical Prediction Tool to Estimate Future Depression Severity and Guide Treatment in Primary Care: User-Centered Design
Caroline Wachtler, Amy Coe, Sandra Davidson, Susan Fletcher, Antonette Mendoza, Leon Sterling, Jane Gunn
BACKGROUND: Around the world, depression is both under- and overtreated. The diamond clinical prediction tool was developed to ass..
Development of a prognostic model for predicting depression severity in adult primary patients with depressive symptoms using the diamond longitudinal study
Patty Chondros, Sandra Davidson, Rory Wolfe, Gail Gilchrist, Christopher Dowrick, Frances Griffiths, Kelsey Hegarty, Helen Herrman, Jane Gunn
BACKGROUND: Depression trajectories among primary care patients are highly variable, making it difficult to identify patients that..
Target-D: a stratified individually randomized controlled trial of the diamond clinical prediction tool to triage and target treatment for depressive symptoms in general practice: study protocol for a randomized controlled trial
Jane Gunn, Caroline Wachtler, Susan Fletcher, Sandra Davidson, Cathrine Mihalopoulos, Victoria Palmer, Kelsey Hegarty, Amy Coe, Elizabeth Murray, Christopher Dowrick, Gavin Andrews, Patty Chondros
BACKGROUND: Depression is a highly prevalent and costly disorder. Effective treatments are available but are not always delivered ..