MAPPING AND TREATING EARLY CLINICAL STAGES OF MENTAL DISORDERS DURING TRANSITION TO ADULTHOOD

Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis

Subash Raj Susai, Colm Healy, David Mongan, Meike Heurich, Jonah F Byrne, Mary Cannon, Gerard Cagney, Kieran Wynne, Connie Markulev, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hickie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft

2022-10-28

Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) in early psychosis. The present s..

Effects of omega-3 polyunsaturated fatty acid supplementation on cognitive functioning in youth at ultra-high risk for psychosis: secondary analysis of the NEURAPRO randomised controlled trial

Nicholas Cheng, Alison McLaverty, Barnaby Nelson, Connie Markulev, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hicikie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler, Swapna Verma, Rebekah Street, Andrew Thompson, Hok Pan Yuen

2022-09-08

BACKGROUND: Cognitive impairments are well-established features of psychotic disorders and are present when individuals are at ult..

Has improved treatment contributed to the declining rate of transition to psychosis in ultra-high-risk cohorts?

MJC Formica, LJ Phillips, JA Hartmann, AR Yung, SJ Wood, A Lin, GP Amminger, PD McGorry, B Nelson

2022-05-01

BACKGROUND: The factors contributing to declining psychotic disorder transition rates in ultra-high-risk populations remain unclea..

Twelve-Month Cognitive Trajectories in Individuals at Ultra-High Risk for Psychosis: A Latent Class Analysis

K Allott, SJ Schmidt, HP Yuen, SJ Wood, B Nelson, C Markulev, S Lavoie, WJ Brewer, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma

2022-01-01

Understanding longitudinal cognitive performance in individuals at ultra-high risk for psychosis (UHR) is important for informing ..

The association of plasma inflammatory markers with omega-3 fatty acids and their mediating role in psychotic symptoms and functioning: An analysis of the NEURAPRO clinical trial

Subash Raj Susai, David Mongan, Colm Healy, Mary Cannon, Barnaby Nelson, Connie Markulev, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schloegelhofer, Stefan Smesny, Ian B Hickie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Swapna Verma, Andrew Thompson

2021-10-08

There is increasing evidence that dysregulation of polyunsaturated fatty acids (FAs) mediated membrane function plays a role in th..

Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

Corrado Sandini, Daniela Zoller, Maude Schneider, Anjali Tarun, Marco Armondo, Barnaby Nelson, Paul G Amminger, Hok Pan Yuen, Connie Markulev, Monica R Schaffer, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hickie, Gregor Emanuel Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler

2021-09-27

Causal interactions between specific psychiatric symptoms could contribute to the heterogenous clinical trajectories observed in e..

Toxoplasma gondii, Herpesviridae and long-term risk of transition to first-episode psychosis in an ultra high-risk sample

E Burkhardt, M Berger, RH Yolken, A Lin, HP Yuen, SJ Wood, SM Francey, A Thompson, PD McGorry, B Nelson, AR Yung, GP Amminger

2021-07-02

BACKGROUND: Ultra high-risk (UHR) criteria were introduced to identify people at imminent risk of developing psychosis. To improve..

Greater preference for eveningness is associated with negative symptoms in an ultra-high risk for psychosis sample

Jashmina J Shetty, Christian Nicholas, Barnaby Nelson, Patrick D McGorry, Suzie Lavoie, Connie Markulev, Miriam R Schafer, Andrew Thompson, Hok Pan Yuen, Alison R Yung, Dorien H Nieman, Lieuwe de Haan, G Paul Amminger, Jessica A Hartmann

2021-02-03

AIM: Investigating biological processes in at-risk individuals may help elucidate the aetiological mechanisms underlying psychosis..

Comparison of erythrocyte omega-3 index, fatty acids and molecular phospholipid species in people at ultra-high risk of developing psychosis and healthy people

Ayedh Alqarni, Todd W Mitchell, Patrick D McGorry, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hickie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler, Swapna Verma, Andrew Thompson

2020-12-01

People classified as ultra-high risk (UHR) of developing psychosis have reduced cellular membrane omega-3 and omega-6 polyunsatura..

Supplementation with the omega-3 long chain polyunsaturated fatty acids: Changes in the concentrations of omega-3 index, fatty acids and molecular phospholipids of people at ultra high risk of developing psychosis

Ayedh Alqarni, Todd W Mitchell, Patrick D McGorry, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schlogelhofer, Stephan Smesny, Ian B Hickie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler, Swapna Verma, Andrew Thompson

2020-12-01

Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) are necessary for optimum mental health, with recent studies showing l..

Do schizotypal or borderline personality disorders predict onset of psychotic disorder or persistent attenuated psychotic symptoms in patients at high clinical risk?

H Hadar, H Zhang, LJ Phillips, GP Amminger, GE Berger, EYH Chen, L de Haan, JA Hartmann, IB Hickie, S Lavoie, C Markulev, PD McGorry, N Mossaheb, DH Nieman, M Nordentoft, A Riecher-Rossler, MR Schafer, M Schloegelhofer, S Smesny, A Thompson

2020-06-01

Cognitive functioning in ultra -high risk for psychosis individuals with and without depression: Secondary analysis of findings from the NEURAPRO randomized clinical trial

Sumudu Rasangi Mallawaarachchi, G Paul Amminger, John Farhall, Luke K Bolt, Barnaby Nelson, Hok Pan Yuen, Patrick D McGorry, Connie Markulev, Miriam R Schaefer, Nilufar Mossaheb, Monika Schloegelhofer, Stefan Smesny, Ian B Hickie, Gregor Emanuel Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Swapna Verma

2020-04-01

Neurocognitive impairments are well established in both ultra-high risk (UHR) for psychosis and major depressive disorder (MDD). D..

Basic symptoms in young people at ultra-high risk of psychosis: Association with clinical characteristics and outcomes

S Youn, LJ Phillips, GP Amminger, G Berger, EYH Chen, L de Haan, JA Hartmann, IB Hickie, S Lavoie, C Markulev, PD McGorry, N Mossaheb, DH Nieman, M Nordentoft, A Riecher-Rossler, MR Schafer, M Schloegelhofer, S Smesny, A Thompson, S Verma

2020-02-01

There has been limited research into the predictive value of basic symptoms and their relationship with other psychopathology in p..

Global research priorities for youth mental health

Cristina Mei, Joanna Fitzsimons, Nicholas Allen, Mario Alvarez-Jimenez, Gunter Paul Amminger, Vivienne Browne, Mary Cannon, Maryann Davis, Barbara Dooley, Ian B Hickie, Srividya Iyer, Eoin Killackey, Ashok Malla, Ian Manion, Steve Mathias, Kerryn Pennell, Rosemary Purcell, Debra Rickwood, Swaran P Singh, Stephen J Wood

2020-02-01

AIM: Over the past two decades, the youth mental health field has expanded and advanced considerably. Yet, mental disorders contin..

The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis

G Paul Amminger, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schloegelhofer, Stephan Smesny, Ian B Hickie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Swapna Verma, Andrew Thompson, Alison Ruth Yung, Patrick D McGorry

2020-02-01

BACKGROUND: NEURAPRO was a multicenter, placebo-controlled trial of long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) (fi..

The prognostic significance of attenuated psychotic symptoms in help-seeking youth

H Hazan, T Spelman, GP Amminger, I Hickie, PD McGorry, LJ Phillips, R Purcell, SJ Wood, AR Yung, B Nelson

2020-01-01

BACKGROUND: Recent findings suggest that attenuated psychotic symptoms (APS) might serve as a risk factor for general mental healt..

Trajectories of symptom severity and functioning over a three-year period in a psychosis high-risk sample: A secondary analysis of the Neurapro trial

Jessica A Hartmann, Stefanie J Schmidt, Patrick D McGorry, Maximus Berger, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Ian B Hickie, Suzie Lavoie, Connie Markulev, Nilufar Mossaheb, Dorien H Nieman, Merete Nordentoft, Andrea Polari, Anita Riecher-Rossler, Miriam R Schafer, Monika Schlogelhofer, Stefan Smesny, Andrew Thompson, Swapna K Verma

2020-01-01

The Ultra-High Risk (UHR) for psychosis group is known to be heterogeneous with diverse outcomes. This study aimed to: 1. Identify..

Aripiprazole compared with placebo for auditory verbal hallucinations in youth with borderline personality disorder: Protocol for the VERBATIM randomized controlled trial

Andrew M Chanen, Jennifer Betts, Henry Jackson, Patrick McGorry, Barnaby Nelson, Sue M Cotton, Cali Bartholomeusz, Martina Jovev, Aswin Ratheesh, Christopher Davey, Christos Pantelis, Louise McCutcheon, Shona Francey, Amit Bhaduri, Danielle Lowe, Victoria Rayner, Katherine Thompson

2019-12-01

AIM: Up to half of patients with borderline personality disorder report auditory verbal hallucinations that are phenomenologically..

The Vitamins in Psychosis Study: A Randomized, Double-Blind, Placebo-Controlled Trial of the Effects of Vitamins B-12, B-6, and Folic Acid on Symptoms and Neurocognition in First-Episode Psychosis

Kelly Allott, Patrick D McGorry, Hok Pan Yuen, Joseph Firth, Tina-Marie Proffitt, Gregor Berger, Paul Maruff, Michaels K O'Regan, Alicia Papas, Timothy CB Stephens, Colin P O'Donnell

2019-07-01

BACKGROUND: Elevated homocysteine is observed in schizophrenia and associated with illness severity. The aim of this study was to ..

Broad clinical high-risk mental state (CHARMS): Methodology of a cohort study validating criteria for pluripotent risk

Jessica A Hartmann, Barnaby Nelson, Rachael Spooner, G Paul Amminger, Andrew Chanen, Christopher G Davey, Meredith McHugh, Aswin Ratheesh, Devi Treen, Hok Pan Yuen, Patrick D McGorry

2019-06-01

AIM: The development of the ultra-high risk (UHR) criteria for psychosis created a new paradigm for the prevention research in psy..

Neurocognition as a predictor of transition to psychotic disorder and functional outcomes in ultra-high risk participants: Findings from the NEURAPRO randomized clinical trial

Luke K Bolt, G Paul Amminger, John Farhall, Patrick D McGorry, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R Schafer, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hickie, Gregor Emanuel Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Swapna Verma, Andrew Thompson

2019-04-01

BACKGROUND: Neurocognitive impairments experienced by individuals at ultra-high risk (UHR) for psychosis are potential predictors ..

Current versus recently resolved attenuated psychotic symptoms: Same level of risk for transition to psychosis?

Simon M Rice, Patrick D McGorry, G Paul Amminger, Barnaby Nelson

2019-02-01

The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth

Chloe de Vos, Andrew Thompson, Paul Amminger, Sarah Bendall, Lieuwe de Haan, Jessica Hartmann, Suzie Lavoie, Connie Markulev, Patrick McGorry, Dorien Nieman, Lisa Phillips, Ulrich Reininghaus, Hok Pan Yuen, Alison Yung, Barnaby Nelson

2019-01-02

Mounting evidence suggests that a history of childhood trauma (CT) is associated with an increased risk of developing a psychotic ..

At-risk studies and clinical antecedents of psychosis, bipolar disorder and depression: a scoping review in the context of clinical staging

Jessica A Hartmann, Barnaby Nelson, Aswin Ratheesh, Devi Treen, Patrick D McGorry

2019-01-01

Identifying young people at risk of developing serious mental illness and identifying predictors of onset of illness has been a fo..

An fMRI study of theory of mind in individuals with first episode psychosis

Cali F Bartholomeusz, Eleni P Ganella, Sarah Whittle, Kelly Allott, Andrew Thompson, Ahmad Abu-Akerl, Henrik Walter, Patrick McGorry, Eoin Killackey, Christos Pantelis, Stephen J Wood

2018-11-30

Theory of mind (ToM), the ability to infer one's own and others' mental states, is the social cognitive process shown to have the ..

Early intervention in youth mental health: progress and future directions

Patrick D McGorry, Cristina Mei

2018-11-01

Early intervention is a fundamental principle in health care and the past two decades have seen it belatedly introduced into the f..

Ultra-high-risk paradigm: lessons learnt and new directions

Patrick D McGorry, Cristina Mei

2018-11-01

Within the embryonic early psychosis field in the early 1990s, the conceptualisation and definition of an at-risk or ultra-high-ri..

Recent Meta-Analyses in the Clinical High Risk for Psychosis Population: Clinical Interpretation of Findings and Suggestions for Future Research

Barnaby Nelson, Gunter Paul Amminger, Patrick Denistoon McGorry

2018-10-12

One of the major advances over the past 20 years in psychiatry is the capacity not only to identify people at incipient risk for p..

Early Intervention-An Implementation Challenge for 21st Century Mental Health Care

Patrick D McGorry, Aswin Ratheesh, Brian O'Donoghue

2018-06-01

"Is "early intervention" in bipolar disorder what it claims to be?' Malhi etal

Patrick D McGorry, Aswin Ratheesh, Michael Berk, Philippe Conus

2018-05-01

Adolescent and Young Adult Male Mental Health: Transforming System Failures Into Proactive Models of Engagement

Simon M Rice, Rosemary Purcell, Patrick D McGorry

2018-03-01

Adolescent and young adult men do poorly on indicators of mental health evidenced by elevated rates of suicide, conduct disorder, ..

Predictors of longer-term outcome in the Vienna omega-3 high-risk study

Nilufar Mossaheb, Miriam R Schaefer, Monika Schloegelhofer, Claudia M Klier, Stefan Smesny, Patrick D McGorry, Maximus Berger, G Paul Amminger

2018-03-01

Longer-term data on ω-3 polyunsaturated fatty acids (PUFA) for prevention of psychosis in (ultra high risk) UHR individuals have i..

Improving outcomes of first-episode psychosis: an overview

Paolo Fusar-Poli, Patrick D McGorry, John M Kane

2017-10-01

Outcomes of psychotic disorders are associated with high personal, familiar, societal and clinical burden. There is thus an urgent..

Staging in bipolar disorder: from theoretical framework to clinical utility

Michael Berk, Robert Post, Aswin Ratheesh, Emma Gliddon, Ajeet Singh, Eduard Vieta, Andre F Carvalho, Melanie M Ashton, Lesley Berk, Susan M Cotton, Patrick D McGorry, Brisa S Fernandes, Lakshmi N Yatham, Seetal Dodd

2017-10-01

Illness staging is widely utilized in several medical disciplines to help predict course or prognosis, and optimize treatment. Sta..

Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study

ME Berger, S Smesny, S-W Kim, CG Davey, S Rice, Z Sarnyai, M Schloegelhofer, MR Schafer, M Berk, PD McGorry, GP Amminger

2017-08-29

While cross-sectional studies suggest that patients with mood disorders have a higher ratio of omega-6 to omega-3 polyunsaturated ..

Longitudinal determinants of client treatment satisfaction in an intensive first-episode psychosis treatment programme

Lisa N Cruz, Emily Kline, Larry J Seidman, Kyle S Minor, Eric C Meyer, Carina Iati, Suzanna V Zimmet, Michelle Friedman-Yakoobian

2017-08-01

AIM: Previous evidence demonstrates that higher treatment satisfaction is strongly associated with improved clinical outcomes and ..

Long-term employment among people at ultra-high risk for psychosis

Jack Cotter, Ashleigh Lin, Richard J Drake, Andrew Thompson, Barnaby Nelson, Patrick McGorry, Stephen J Wood, Alison R Yung

2017-06-01

BACKGROUND: Psychotic disorders are associated with high rates of sustained unemployment, however, little is known about the long-..

Negative Psychosis Prevention Trials Reply

Patrick D McGorry, Barnaby Nelson, Paul Amminger

2017-06-01

Quetiapine v. lithium in the maintenance phase following a first episode of mania: randomised controlled trial

Michael Berk, Rothanthi Daglas, Orwa Dandash, Murat Yucel, Lisa Henry, Karen Hallam, Craig Macneil, Melissa Hasty, Christos Pantelis, Brendan P Murphy, Linda Kader, Saji Damodaran, Michael TH Wong, Philippe Conus, Aswin Ratheesh, Patrick D McGorry, Sue M Cotton

2017-06-01

BackgroundLithium and quetiapine are considered standard maintenance agents for bipolar disorder yet it is unclear how their effic..

Back to the future: Schizophrenia in retrospect and prospect

Patrick D McGorry

2017-05-01

Novel biotherapies are needed in youth mental health

G Paul Amminger, Maximus Berger, Simon M Rice, Christopher G Davey, Miriam R Schafer, Patrick D McCorry

2017-04-01

Adverse effects and lack of efficacy in a significant number of patients limit pharmaceutical interventions in youth psychiatry. T..

Erythrocyte glutathione levels as long-term predictor of transition to psychosis

S Lavoie, M Berger, M Schloegelhofer, MR Schaefer, S Rice, S-W Kim, J Hesse, PD McGorry, S Smesny, GP Amminger

2017-03-21

A high proportion of individuals deemed at elevated risk for psychosis will actually never progress to develop the illness. Pharma..

Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis

Renate LEP Reniers, Ashleigh Lin, Alison R Yung, Nikolaos Koutsouleris, Barnaby Nelson, Vanessa L Cropley, Dennis Velakoulis, Patrick D McGorry, Christos Pantelis, Stephen J Wood

2017-03-01

Most individuals at ultra-high risk (UHR) for psychosis do not transition to frank illness. Nevertheless, many have poor clinical ..

Multi-center MRI prediction models: Predicting sex and illness course in first episode psychosis patients

Mireille Nieuwenhuis, Hugo G Schnack, Neeltje E van Haren, Julia Lappin, Craig Morgan, Antje A Reinders, Diana Gutierrez-Tordesillas, Roberto Roiz-Santianez, Maristela S Schaufelberger, Pedro G Rosa, Marcus V Zanetti, Geraldo F Busatto, Benedicto Crespo-Facorro, Patrick D McGorry, Dennis Velakoulis, Christos Pantelis, Stephen J Wood, Rene S Kahn, Janaina Mourao-Miranda, Paola Dazzan

2017-01-15

Structural Magnetic Resonance Imaging (MRI) studies have attempted to use brain measures obtained at the first-episode of psychosi..

Effect of omega-3 Polyunsaturated Fatty Acids in Young People at Ultrahigh Risk for Psychotic Disorders The NEURAPRO Randomized Clinical Trial

Patrick D McGorry, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R Schaefer, Nilufar Mossaheb, Monika Schloegelhofer, Stephan Smesny, Ian B Hickie, Gregor Emanuel Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler, Swapna Verma, Andrew Thompson, Alison Ruth Yung, G Paul Amminger

2017-01-01

IMPORTANCE: A promising treatment to prevent onset and improve outcomes in patients at ultrahigh risk for psychosis is dietary sup..

Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

Jessica A Hartmann, Patrick D McGorry, Stefanie J Schmidt, G Paul Amminger, Hok Pan Yuen, Connie Markulev, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Ian B Hickie, Suzie Lavoie, Meredith J McHugh, Nilufar Mossaheb, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Miriam R Schafer, Monika Schloegelhofer, Stefan Smesny, Andrew Thompson

2017-01-01

BACKGROUND: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis...

Differential expression of the inflammation marker IL12p40 in the at-risk mental state for psychosis: a predictor of transition to psychotic disorder?

Melanie Focking, Patrick Dicker, Lorna M Lopez, Mary Cannon, Miriam R Schafer, Patrick D McGorry, Stefan Smesny, David R Cotter, G Paul Amminger

2016-09-20

BACKGROUND: The identification of biomarkers of transition from the at-risk mental state (ARMS) to psychotic disorder is important..

White matter integrity in individuals at ultra-high risk for psychosis: a systematic review and discussion of the role of polyunsaturated fatty acids

Nandita Vijayakumar, Cali Bartholomeusz, Thomas Whitford, Daniel F Hermens, Barnaby Nelson, Simon Rice, Sarah Whittle, Christos Pantelis, Patrick McGorry, Miriam R Schafer, G Paul Amminger

2016-08-11

BACKGROUND: Schizophrenia is thought to be a neurodevelopmental disorder with pathophysiological processes beginning in the brain ..

Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F): A randomized, double-blind, placebo-controlled treatment trial

Simon M Rice, Ian B Hickie, Alison R Yung, Andrew Mackinnon, Michael Berk, Christopher Davey, Daniel F Hermens, Sarah E Hetrick, Alexandra G Parker, Miriam R Schafer, Patrick D McGorry, G Paul Amminger

2016-08-01

AIM: US authorities have recommended 'black-box' warnings for antidepressants because of the increased risk of suicidality for ind..

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

Vanessa L Cropley, Ashleigh Lin, Barnaby Nelson, Renate LEP Reniers, Alison R Yung, Cali F Bartholomeusz, Paul Klauser, Dennis Velakoulis, Patrick McGorry, Stephen J Wood, Christos Pantelis

2016-06-01

Beyond Clinical Remission in First Episode Psychosis: Thoughts on Antipsychotic Maintenance vs. Guided Discontinuation in the Functional Recovery Era

M Alvarez-Jimenez, B O'Donoghue, A Thompson, JF Gleeson, S Bendall, C Gonzalez-Blanch, E Killackey, L Wunderink, PD McGorry

2016-05-01

Treatment guidelines for first episode psychosis (FEP) recommend at least 1 year of antipsychotic treatment following remission; h..

Cognitive intervention in early psychosis - preserving abilities versus remediating deficits

Christos Pantelis, Cassandra Wannan, Cali F Bartholomeusz, Kelly Allott, Patrick D McGorry

2015-08-01

Remediation strategies have focused on a deficits model to plan restorative interventions, with inconsistent results. Here, we pro..

Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study

G Paul Amminger, Miriam R Schaefer, Monika Schloegelhofer, Claudia M Klier, Patrick D McGorry

2015-08-01

Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural development and function. As key components of bra..

The relationship between stress, HPA axis functioning and brain structure in first episode psychosis over the first 12 weeks of treatment

Renate LEP Reniers, Belinda Garner, Christina Phassouliotis, Lisa J Phillips, Connie Markulev, Christos Pantelis, Sarah Bendall, Patrick D McGorry, Stephen J Wood

2015-02-28

Stress and abnormal hypothalamic-pituitary-adrenal axis functioning have been implicated in the early phase of psychosis and may p..

Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids

GP Amminger, A Mechelli, S Rice, S-W Kim, CM Klier, RK McNamara, M Berk, PD McGorry, MR Schaefer

2015-01-13

Previous efforts in the prospective evaluation of individuals who experience attenuated psychotic symptoms have attempted to isola..

Long-term follow-up of all-cause and unnatural death in young people with first-episode psychosis

Kally Yuen, Susy M Harrigan, Andrew J Mackinnon, Meredith G Harris, Hok Pan Yuen, Lisa P Henry, Henry J Jackson, Helen Herrman, Patrick D McGorry

2014-10-01

OBJECTIVE: To determine mortality-related estimates and causes of death in young people with first-episode psychosis (FEP), and to..