PROMOTING AND ADVANCING MIDLIFE HEALTH IN WOMEN

Grant number: 1058935 | Funding period: 2014 - 2020

Completed

Abstract

Australia has an ageing population and women spend around one third of their lives after menopause. Optimising physical and emotional health at menopause is a national health priority, and improving the health of women will improve health for the community. This research program is targeted at improving physical and mental health for midlife and older women. Findings will be translated into changes in policy and practice which improve the lives of women in Australia and worldwide

Related publications (22)

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What happens after menopause? (WHAM): A prospective controlled study of vasomotor symptoms and menopause-related quality of life 12 months after premenopausal risk-reducing salpingo-oophorectomy

Martha Hickey, Katrina M Moss, Efrosinia O Krejany, C David Wrede, Alison Brand, Judy Kirk, Heather L Symecko, Susan M Domchek, Trevor Tejada-Berges, Alison Trainer, Gita D Mishra

2021-10-07

OBJECTIVE: To measure menopausal symptoms and quality of life up to 12 months after risk-reducing salpingo-oophorectomy (RRSO) and..

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What happens after menopause? (WHAM): A prospective controlled study of sleep quality up to 12 months after premenopausal risk-reducing salpingo-oophorectomy

Martha Hickey, Katrina M Moss, Efrosinia O Krejany, C David Wrede, Susan M Domchek, Judy Kirk, Alison Brand, Alison Trainer, Gita D Mishra, Fiona C Baker

2021-07-24

OBJECTIVE: Sleep difficulties impair function and increase the risk of depression at menopause and premenopausal oophorectomy may ..

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A prospective controlled study of sexual function and sexually related personal distress up to 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy

Rakibul M Islam, Susan R Davis, Robin J Bell, Trevor Tejada-Berges, Caspar David Wrede, Susan M Domchek, Bettina Meiser, Judy Kirk, Efrosinia O Krejany, Martha Hickey

2021-07-01

OBJECTIVE: Premenopausal risk-reducing bilateral salpingo-oophorectomy (RRBSO) may impair sexual function, but the nature and degr..

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What Happens After Menopause? (WHAM): A prospective controlled study of cardiovascular and metabolic risk 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy

Martha Hickey, Katrina M Moss, Gita D Mishra, Efrosinia O Krejany, Susan M Domchek, John D Wark, Alison Trainer, Robert A Wild

2021-06-19

OBJECTIVE: To prospectively measure cardiometabolic risk 12 months after premenopausal risk-reducing bilateral salpingo-oophorecto..

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How common is add-on use and how do patients decide whether to use them? A national survey of IVF patients

S Lensen, K Hammarberg, A Polyakov, J Wilkinson, S Whyte, M Peate, M Hickey

2021-05-04

STUDY QUESTION: What is the prevalence and pattern of IVF add-on use in Australia? SUMMARY ANSWER: Among women having IVF in the l..

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What happens after menopause(WHAM): A prospective controlled study of depression and anxiety up to 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy

Martha Hickey, Katrina M Moss, Alison Brand, C David Wrede, Susan M Domchek, Bettina Meiser, Gita D Mishra, Hadine Joffe

2021-04-24

OBJECTIVE: Risk-reducing bilateral salpingo-oophorectomy (RRBSO) substantially reduces ovarian cancer risk in women with pathogeni..

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Loss of bone density and bone strength following premenopausal risk-reducing bilateral salpingo-oophorectomy: a prospective controlled study (WHAM Study)

H Jiang, DL Robinson, PVS Lee, EO Krejany, CJ Yates, M Hickey, JD Wark

2020-08-27

UNLABELLED: Prophylactic oophorectomy is recommended for women at high risk for ovarian cancer, but the associated impact on bone ..

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ApoB48-Lipoproteins Are Associated with Cardiometabolic Risk in Adolescents with and without Polycystic Ovary Syndrome

Donna F Vine, Lawrence J Beilin, Sally Burrows, Rae-Chi Huang, Martha Hickey, Roger Hart, Spencer D Proctor, Trevor A Mori

2020-08-01

CONTEXT: Adolescents with polycystic ovary syndrome (PCOS) have increased incidence of cardiometabolic risk factors including dysl..

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Variation in menopausal vasomotor symptoms outcomes in clinical trials: A systematic review

S Iliodromiti, W Wang, MA Lumsden, MS Hunter, R Bell, G Mishra, M Hickey

2019-11-13

BACKGROUND: There is substantial variation in how menopausal vasomotor symptoms are reported and measured among intervention studi..

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Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort study

Chi Le-Ha, Lawrence J Beilin, Sally Burrows, Rae-Chi Huang, Martha Hickey, Trevor A Mori, Roger J Hart

2018-12-21

OBJECTIVE: This study aimed to examine the association between age at menarche and a range of cardiovascular disease (CVD) risk fa..

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Genome-wide association study identifies nine novel loci for 2D: 4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

Nicole M Warrington, Enisa Shevroja, Gibran Hemani, Pirro G Hysi, Yunxuan Jiang, Adam Auton, Cindy G Boer, Massimo Mangino, Carol A Wang, John P Kemp, George McMahon, Carolina Medina-Gomez, Martha Hickey, Katerina Trajanoska, Dieter Wolke, M Arfan Ikram, Grant W Montgomery, Janine F Felix, Margaret J Wright, David A Mackey

2018-06-01

The ratio of the length of the index finger to that of the ring finger (2D:4D) is sexually dimorphic and is commonly used as a non..

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Exploring knowledge, attitudes and experience of genitourinary symptoms in women with early breast cancer on adjuvant endocrine therapy

M Sousa, M Peate, C Lewis, S Jarvis, A Willis, M Hickey, M Friedlander

2018-03-01

Clinical trials of adjuvant endocrine therapy in women with early breast cancer have consistently reported that genitourinary symp..

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Sexual inactivity in partnered female cancer survivors

Jennifer L Marino, Christobel M Saunders, Martha Hickey

2017-11-01

OBJECTIVE: To measure sexual activity in a clinic population of partnered female cancer survivors, and to better understand reason..

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What Happens After Menopause? (WHAM): protocol for a prospective, multicentre, age-matched cohort trial of risk-reducing bilateral salpingo-oophorectomy in high-risk premenopausal women

Martha Hickey, Alison Trainer, Sabine Braat, Mary-Ann Davey, Efrosinia Krejany, John Wark

2017-11-01

INTRODUCTION: Women at high inherited risk of ovarian cancer are advised to undergo risk-reducing bilateral salpingo-oophorectomy ..

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Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

Lisa M Unwin, Ildiko Bruz, Murray T Maybery, Victoria Reynolds, Natalie Ciccone, Cheryl Dissanayake, Martha Hickey, Andrew JO Whitehouse

2017-07-01

There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder (ASD) have an atypical pattern of cry..

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Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys

Oyekoya T Ayonrinde, Leon A Adams, Dorota A Doherty, Trevor A Mori, Lawrence J Beilin, Wendy H Oddy, Martha Hickey, Deborah M Sloboda, John K Olynyk, Roger Hart

2016-05-01

BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adi..

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Mechanisms of HIV Transmission in Depo-Provera Users: The Likely Role of Hypoestrogenism

Martha Hickey, Jennifer L Marino, Gilda Tachedjian

2016-01-01

Almost half of new HIV infections worldwide occur in women, and vaginal intercourse is the most common mode of transmission. Accum..

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How Is the Number of Primordial Follicles in the Ovarian Reserve Established?

John K Findlay, Karla J Hutt, Martha Hickey, Richard A Anderson

2015-11-01

The number of primordial follicles in the ovarian reserve is an important determinant of the length of the ovarian lifespan, and t..

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Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

Lauren P Hollier, Jeffrey A Keelan, Esha SL Jamnadass, Murray T Maybery, Martha Hickey, Andrew JO Whitehouse

2015-02-01

BACKGROUND: Ratio of second digit length to fourth digit length (2D:4D) has been extensively used in human and experimental resear..

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Childhood Behavior Problems and Age at First Sexual Intercourse: A Prospective Birth Cohort Study

S Rachel Skinner, Monique Robinson, Michael A Smith, Spring Chenoa Cooper Robbins, Eugen Mattes, Jeffrey Cannon, Susan L Rosenthal, Jennifer L Marino, Martha Hickey, Dorota A Doherty

2015-02-01

BACKGROUND AND OBJECTIVES: Early first sexual intercourse (FSI) is a risk factor for unplanned teenage pregnancy, sexually transmi..

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Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

Lauren P Hollier, Murray T Maybery, Jeffrey A Keelan, Martha Hickey, Andrew JO Whitehouse

2014-12-01

Two competing theories address the influence of foetal testosterone on cerebral laterality: one proposing exposure to high foetal ..

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Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development

Lauren P Hollier, Jeffrey A Keelan, Martha Hickey, Murray T Maybery, Andrew JO Whitehouse

2014-01-01

Accurately measuring hormone exposure during prenatal life presents a methodological challenge and there is currently no "gold sta..