Building macroscale models from microscale probabilistic models
Grant number: DP140100339 | Funding period: 2014 - 2019
Spatial patterns arise in biological and physical processes. Understanding how local individual-based functions, such as movement and interactions between individuals, give rise to global spatial distributions and patterns in populations of individuals is generating much interest. Probabilistic agent-based models provide information about the movement of individuals, whereas continuum models provide information about the global properties, such as spread of populations. This project will provide tools for determining the connection between the two types of models, thereby linking the behaviour on microscopic and macroscopic scales.
Related publications (13)
Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model
Luis Almeida, Patrizia Bagnerini, Giulia Fabrini, Barry D Hughes, Tommaso Lorenzi
We consider a phenotype-structured model of evolutionary dynamics in a population of cancer cells exposed to the action of a cytot..
Is cell migration or proliferation dominant in the formation of linear arrays of oligodendrocytes?
DM Walsh, PT Roth, WR Holmes, KA Landman, TD Merson, BD Hughes
Oligodendrocytes are the myelin-producing cells of the central nervous system that are responsible for electrically insulating axo..