MINIMALLY-INVASIVE BRAIN MACHINE INTERFACE FOR ROBOTIC LIMB CONTROL
Grant number: 1062532 | Funding period: 2014 - 2018
Persons affected by quadriplegia and hemiplegia from stroke and spinal cord injury have few treatment options. Brain Machine Interfaces (BMIs) reconnect brain to a prosthetic limb, bypassing damaged nervous system. Our group has developed a BMI that can be implanted minimally-invasively, inside a blood vessel within the brain. We propose to evaluate this device in animal studies, and continue on to a human clinical trial pilot study. The aim is to restore mechanical control over the physical environment for a paralysed patient.
Related publications (6)
Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience.
Thomas J Oxley, Peter E Yoo, Gil S Rind, Stephen M Ronayne, CM Sarah Lee, Christin Bird, Victoria Hampshire, Rahul P Sharma, Andrew Morokoff, Daryl L Williams, Christopher MacIsaac, Mark E Howard, Lou Irving, Ivan Vrljic, Cameron Williams, Sam E John, Frank Weissenborn, Madeleine Dazenko, Anna H Balabanski, David Friedenberg
BACKGROUND: Implantable brain-computer interfaces (BCIs), functioning as motor neuroprostheses, have the potential to restore volu..
Distinct Neural Correlates Underlie Inhibitory Mechanisms of Motor Inhibition and Motor Imagery Restraint
PE Yoo, TJ Oxley, MA Hagan, S John, SM Ronayne, GS Rind, AM Brinded, NL Opie, BA Moffat, YT Wong
There is evidence to suggest that motor execution and motor imagery both involve planning and execution of the same motor plan, ho..
Neural Stimulation with an Endovascular Brain-Machine Interface
NL Opie, SE John, G Gerboni, GS Rind, TJH Lovell, SM Ronayne, YT Wong, CN May, DB Grayden, TJ Oxley
Stimulation of deep cortical structures has been demonstrated to provide symptomatic alleviation to people with depression, Parkin..
Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an endovascular stent
Nicholas L Opie, Sam E John, Gil S Rind, Stephen M Ronayne, Yan T Wong, Giulia Gerboni, Peter E Yoo, Timothyj H Lovell, Theodore CM Scordas, Stefan L Wilson, Anthony Dornom, Thomas Vale, Terence J O'brien, David B Grayden, Clive N May, Thomasj Oxley
Development and Implementation of a Corriedale Ovine Brain Atlas for Use in Atlas-Based Segmentation
Kishan Andre Liyanage, Christopher Steward, Bradford Armstrong Moffat, Nicholas Lachlan Opie, Gil Simon Rind, Sam Emmanuel John, Stephen Ronayne, Clive Newton May, Terence John O'Brien, Marjorie Eileen Milne, Thomas James Oxley