KERALA DIABETES PREVENTION PROGRAM (K-DPP): A CLUSTER RCT OF ITS EFFECTIVENESS AND COST-EFFECTIVENESS
Grant number: 1005324 | Funding period: 2014 - 2017
The prevalence of type 2 diabetes mellitus (T2DM) in developing countries has increased dramatically. Action is now urgently required to develop targeted, low cost intervention programs to prevent T2DM. The Kerala Diabetes Prevention Program (K-DPP) is a cluster randomized trial in a rural area of Thiruvananthapuram district in Kerala State, India, of a culturally appropriate locality-based group diabetes intervention targeting individuals (aged 30-60 years) at ‘high risk’ of developing T2DM.
Related publications (20)
Knowledge of Diabetes among Adults at High Risk for Type 2 Diabetes in the Trivandrum District of Kerala, India
Thirunavukkarasu Sathish, Kavumpurathu Raman Thankappan, Jeemon Panniyammakal, Brian Oldenburg
<jats:p>We aimed to study the knowledge of diabetes among individuals with a high risk for developing type 2 diabetes in the Triva..
Effects of a lifestyle intervention on depression and anxiety among adults at risk for diabetes in India: A secondary analysis of the Kerala Diabetes Prevention Program
Leslie CM Johnson, Tilahun Haregu, Thirunavukkarasu Sathish, Jeroen De Man, Allissa Desloge, Pilvikki Absetz, Emily D Williams, Kavumpurathu Raman Thankappan, Brian Oldenburg
The impact of lifestyle interventions on diabetes and mental health conditions have been documented among people with diabetes. Ho..
Associations between Dietary Patterns and Cardiometabolic Risk Factors-A Longitudinal Analysis among High-Risk Individuals for Diabetes in Kerala, India
Yingting Cao, Quan Huynh, Nitin Kapoor, Panniyammakal Jeemon, Gabrielli Thais de Mello, Brian Oldenburg, Kavumpurathu Raman Thankappan, Thirunavukkarasu Sathish
The association between dietary patterns and cardiometabolic risk factors is not well understood among adults in India, particular..
Determinants of Health Service Utilization Among Adults at High Risk of Developing Type 2 Diabetes in Kerala, India
Phoebe Hone, Jim Black, Thirunavukkarasu Sathish, Nitin Kapoor, Yingting Cao, Tilahun Haregu, Kavumpurathu R Thankappan, Brian Oldenburg
The purpose of this study was to examine the determinants of health service utilization in a population at high risk of developing..
Factors Associated With Hypertension Awareness, Treatment, and Control Among Adults in Kerala, India
Yingting Cao, Thirunavukkarasu Sathish, Tilahun Haregu, Yu Wen, Gabrielli Thais de Mello, Nitin Kapoor, Brian Oldenburg
Background: Hypertension, the most significant risk factor for cardiovascular disease, is an increasing contributor to global heal..
The relationship between common mental disorders and incident diabetes among participants in the Kerala Diabetes Prevention Program (K-DPP)
Leslie CM Johnson, Allissa Desloge, Thirunavukkarasu Sathish, Emily D Williams, Pilvikki Absetz, Tilahun Haregu, Jeroen De Man, Kavumpurathu Raman Thankappan, Brian Oldenburg
This study aims to describe the prevalence of depression and anxiety among a population sample of people at high risk for type 2 d..
Are the PHQ-9 and GAD-7 Suitable for Use in India? A Psychometric Analysis
Jeroen De Man, Pilvikki Absetz, Thirunavukkarasu Sathish, Allissa Desloge, Tilahun Haregu, Brian Oldenburg, Leslie CM Johnson, Kavumpurathu Raman Thankappan, Emily D Williams
BACKGROUND: Cross-cultural evidence on the factorial structure and invariance of the PHQ-9 and the GAD-7 is lacking for South Asia..
Effects of a lifestyle intervention on cardiovascular risk among high-risk individuals for diabetes in a low- and middle-income setting: Secondary analysis of the Kerala Diabetes Prevention Program
Mojtaba Lotfaliany, Thirunavukkarasu Sathish, Jonathan Shaw, Emma Thomas, Robyn Jennifer Tapp, Nitin Kapoor, Kavumpurathu Raman Thankappan, Brian Oldenburg
We aimed to examine whether a lifestyle intervention was effective in reducing cardiovascular disease (CVD) risk in individuals at..
Cost-effectiveness of a lifestyle intervention in high-risk individuals for diabetes in a low- and middle-income setting: Trial-based analysis of the Kerala Diabetes Prevention Program
Thirunavukkarasu Sathish, Brian Oldenburg, Kavumpurathu R Thankappan, Pilvikki Absetz, Jonathan E Shaw, Robyn J Tapp, Paul Z Zimmet, Sajitha Balachandran, Suman S Shetty, Zahra Aziz, Ajay Mahal
BACKGROUND: Data on the cost-effectiveness of lifestyle-based diabetes prevention programs are mostly from high-income countries, ..
Prevalence of normal weight obesity and its associated cardio-metabolic risk factors - Results from the baseline data of the Kerala Diabetes Prevention Program (KDPP)
Nitin Kapoor, Mojtaba Lotfaliany, Thirunavukkarasu Sathish, Kavumpurathu R Thankappan, Nihal Thomas, John Furler, Brian Oldenburg, Robyn J Tapp
BACKGROUND: Cardiometabolic disorders are frequently observed among those who have obesity as measured by body mass index (BMI). H..
Effect of a Peer-led Lifestyle Intervention on Individuals With Normal Weight Obesity: Insights From the Kerala Diabetes Prevention Program
Nitin Kapoor, Mojtaba Lotfaliany, Thirunavukkarasu Sathish, Kavumpurathu R Thankappan, Robyn J Tapp, Nihal Thomas, John Furler, Brian Oldenburg
PURPOSE: Normal weight obesity (NWO) is a unique phenotype of obesity associated with high cardiovascular mortality. There is limi..
Obesity indicators that best predict type 2 diabetes in an Indian population: insights from the Kerala Diabetes Prevention Program
Nitin Kapoor, Mojtaba Lotfaliany, Thinmavukkarasu Sathish, KR Thankappan, Nihal Thomas, John Furler, Brian Oldenburg, Robyn J Tapp
Obesity indicators are known to predict the presence of type 2 diabetes mellitus (T2DM); however, evidence for which indicator bes..
Participant recruitment into a community-based diabetes prevention trial in India: Learnings from the Kerala Diabetes Prevention Program
Thirunavukkarasu Sathish, Zahra Aziz, Pilvikki Absetz, Kavumpurathu Raman Thankappan, Robyn Jennifer Tapp, Sajitha Balachandran, Suman Surendra Shetty, Brian Oldenburg
BACKGROUND: Data on participant recruitment into diabetes prevention trials are limited in low- and middle-income countries (LMICs..
Targeted screening for prediabetes and undiagnosed diabetes in a community setting in India
Thirunavukkarasu Sathish, Jonathan E Shaw, Robyn J Tapp, Rory Wolfe, Kavumpurathu R Thankappan, Sajitha Balachandran, Brian Oldenburg
BACKGROUND AND OBJECTIVES: Data to support the use of risk scores in screening programs to detect people with prediabetes and undi..
A group-based lifestyle intervention for diabetes prevention in low- and middle-income country: implementation evaluation of the Kerala Diabetes Prevention Program
Zahra Aziz, Elezebeth Mathews, Pilvikki Absetz, Thirunavukkarasu Sathish, John Oldroyd, Sajitha Balachandran, Suman S Shetty, KR Thankappan, Brian Oldenburg
BACKGROUND: While several efficacy trials have demonstrated diabetes risk reduction through targeting key lifestyle behaviours, th..
A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program
Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg
BACKGROUND: The major efficacy trials on diabetes prevention have used resource-intensive approaches to identify high-risk individ..
Cultural adaptation of a peer-led lifestyle intervention program for diabetes prevention in India: the Kerala diabetes prevention program (K-DPP)
Elezebeth Mathews, Emma Thomas, Pilvikki Absetz, Fabrizio D'Esposito, Zahra Aziz, Sajitha Balachandran, Meena Daivadanam, Kavumpurathu Raman Thankappan, Brian Oldenburg
BACKGROUND: Type 2 diabetes mellitus (T2DM) is now one of the leading causes of disease-related deaths globally. India has the wor..
Baseline characteristics of participants in the Kerala Diabetes Prevention Program: a cluster randomized controlled trial of lifestyle intervention in Asian Indians
T Sathish, B Oldenburg, RJ Tapp, JE Shaw, R Wolfe, B Sajitha, F D'Esposito, P Absetz, E Mathews, PZ Zimmet, KR Thankappan
AIMS: To describe the baseline characteristics of participants in the Kerala Diabetes Prevention Program. METHODS: The Kerala Diab..
Cluster randomised controlled trial of a peer-led lifestyle intervention program: study protocol for the Kerala diabetes prevention program
Thirunavukkarasu Sathish, Emily D Williams, Naanki Pasricha, Pilvikki Absetz, Paula Lorgelly, Rory Wolfe, Elezebeth Mathews, Zahra Aziz, Kavumpurathu Raman Thankappan, Paul Zimmet, Edwin Fisher, Robyn Tapp, Bruce Hollingsworth, Ajay Mahal, Jonathan Shaw, Damien Jolley, Meena Daivadanam, Brian Oldenburg
BACKGROUND: India currently has more than 60 million people with Type 2 Diabetes Mellitus (T2DM) and this is predicted to increase..
Lifestyle change in Kerala, India: needs assessment and planning for a community-based diabetes prevention trial
Meena Daivadanam, Pilvikki Absetz, Thirunavukkarasu Sathish, KR Thankappan, Edwin B Fisher, Neena Elezebeth Philip, Elezebeth Mathews, Brian Oldenburg
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) has become a major public health challenge in India. Factors relevant to the developme..