Cell Death Pathway - A Novel Target for Anthelmintics for Livestock

Early-stage anthelmintic discovery: Integrating phenotype, target and mechanism

AC Taki, BE Sleebs, TNC Wells, J Keiser, RB Gasser

2026-12-01

Parasitic helminth infections impose major burdens on human and animal health, and increasing anthelmintic resistance reinforces t..

From cell culture to cellular biology in animal-parasitic nematodes: Biotechnological advances

T Wang, RB Gasser

2026-12-01

Animal-parasitic nematodes are pathogens of medical and veterinary importance, yet their cellular biology remains poorly resolved ..

Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus

Y Shen, ND Young, J Song, BE Sleebs, BCH Chang, EF Lee, WD Fairlie, RB Gasser

2026-12-01

Background: Programmed cell death (or apoptosis) is a fundamental process in metazoans, extensively characterised in mammals and o..

Intrinsic apoptosis in nematodes: Evolutionary plasticity and biotechnological opportunities

M Kaethner, ND Young, EF Lee, WD Fairlie, BE Sleebs, BCH Chang, RB Gasser

2026-09-01

Intrinsic apoptosis is a form of programmed cell death that underpins development, tissue homeostasis and stress responses across ..