Development Of Dynamin Inhibitors As Novel Therapies For Epilepsy

Grant number: 571076 | Funding period: 2009 - 2011

Completed

Abstract

Epilepsy affects 1% of people, but 30% do not respond to current anti-epileptic drugs (AEDs). Traditional drug discovery has not improved this situation. Our team discovered two exciting new targets for design of better AEDs. One of them blocks seizure in animals. Our aim is to determine how well they work in true animal models of epilepsy. If successful, this will accelerate development of new AEDs with less side-effects, benefiting large sectors of the Australian community.

Researchers