Role Of Neurogenesis In Clinical Recovery From Depression During Ect: Application Of A Novel In Vivo Magnetic Resonance Spectroscopy Technology

Grant number: 1004152 | Funding period: 2011 - 2013



Neurogenesis refers to the generation of new brain cells, which is now known to continue well into adulthood. On the basis of animal studies, deficiencies in neurogenesis have been implicated in development of depression, and stimulation of neurogenesis proposed as one of the ways that anti-depressants may work. Using the latest technological advances in brain imaging, we will for the first time assess the merit of these theories in humans with depression before and after treatment.