ARC CENTRE OF EXCELLENCE IN CONVERGENT BIO–NANO SCIENCE AND TECHNOLOGY

Grant number: CE140100036 | Funding period: 2014 - 2021

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Abstract

The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an..

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Related publications (16)

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Polyphenol-Based Nanoparticles for Intracellular Protein Delivery via Competing Supramolecular Interactions.

Yiyuan Han, Jiajing Zhou, Yingjie Hu, Zhixing Lin, Yutian Ma, Joseph J Richardson, Frank Caruso

2020-10-27

Intracellular delivery of proteins is a promising strategy for regulating cellular behavior and therefore has attracted interest f..

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Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies

Zachary H Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B Howard, Nicholas L Fletcher, Adrian V Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W Boyd, Stephen M Mahler, Linda J Richards, Frank Caruso, Kristofer J Thurecht

2020-05-27

Increasing accumulation and retention of nanomedicines within tumor tissue is a significant challenge, particularly in the case of..

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Physically-plausible modelling of biomolecular systems: A simplified, energy-based model of the mitochondrial electron transport chain

Peter J Gawthrop, Peter Cudmore, Edmund J Crampin

2020-05-21

Advances in systems biology and whole-cell modelling demand increasingly comprehensive mathematical models of cellular biochemistr..

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Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation.

Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Yi Ju, Wenbo Jiang, Verena C Wimmer, Brigette C Duckworth, Joanna R Groom, Frank Caruso, Masaru Kanekiyo, Stephen J Kent, Adam K Wheatley

2020-05-21

Protein-based, self-assembling nanoparticles elicit superior immunity compared with soluble protein vaccines, but the immune mecha..

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Unraveling Biointeractions with Nanoengineered Hydrogel Particles

Frank Caruso

2019-06-03

Oral presentation at Summit on Functional Nanocolloids

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Link between Low-Fouling and Stealth: A Whole Blood Biomolecular Corona and Cellular Association Analysis on Nanoengineered Particles

Alessia CG Weiss, Hannah G Kelly, Matthew Faria, Quinn A Besford, Adam K Wheatley, Ching-Seng Ang, Edmund J Crampin, Frank Caruso, Stephen J Kent

2019-05-28

Upon exposure to human blood, nanoengineered particles interact with a multitude of plasma components, resulting in the formation ..

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Nebulization of Phenolic Capsules for Pulmonary Delivery

Christina Cortez-Jugo, Yi Ju, Leslie Yeo, Christoph Hagemeyer, Frank Caruso

2018-11-30

Oral presentation at ARC Centre of Excellence in Convergent Bio-Nano Science and Technology Annual Research Workshop

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Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles

Quinn A Besford, Yi Ju, Ting-Yi Wang, Gyeongwon Yun, PavelV Cherepanov, Christoph E Hagemeyer, Francesca Cavalieri, Frank Caruso

2018-09-27

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Glycogen-nucleic acid constructs for gene silencing in multicellular tumor spheroids

Marcin Wojnilowicz, Quinn A Besford, Yun-Long Wu, Xian Jun Loh, Julia A Braunger, Agata Glab, Christina Cortez-Jugo, Frank Caruso, Francesca Cavalieri

2018-09-01

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Synthesis of Metal Nanoparticles in Metal-Phenolic Networks: Catalytic and Antimicrobial Applications of Coated Textiles

Gyeongwon Yun, Shuaijun Pan, Ting-Yi Wang, Junling Guo, Joseph J Richardson, Frank Caruso

2018-03-07

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Metal-Organic Frameworks for Cell and Virus Biology: A Perspective

Raffaele Ricco, Weibin Liang, Shaobo Li, Jeremiah J Gassensmith, Frank Caruso, Christian Doonan, Paolo Falcaro

2018-01-01

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A Decade of the Protein Corona

Pu Chun Ke, Sijie Lin, Wolfgang J Parak, Thomas P Davis, Frank Caruso

2017-12-01

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Templated Polymer Replica Nanoparticles to Facilitate Assessment of Material-Dependent Pharmacokinetics and Biodistribution

Danzi Song, Jiwei Cui, Huanli Sun, Tri-Hung Nguyen, Sheilajen Alcantara, Robert De Rose, Stephen J Kent, Christopher JH Porter, Frank Caruso

2017-10-04

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A Partially Graphitic Mesoporous Carbon Membrane with Three Dimensionally Networked Nanotunnels for Ultrasensitive Electrochemical Detection

Cong Fu, Deliang Yi, Chao Deng, Xingdong Wang, Weijia Zhang, Yi Tang, Frank Caruso, Yajun Wang

2017-06-27

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The complexities and caveats of lineage tracing in the mammary gland

Anne C Rios, Nai Yang Fu, Joseph Cursons, Geoffrey J Lindeman, Jane E Visvader

2016-11-25

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Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

J Cursons, KJ Leuchowius, M Waltham, E Tomaskovic-Crook, M Foroutan, CP Bracken, A Redfern, EJ Crampin, I Street, MJ Davis, EW Thompson

2015-01-01