ARC CENTRE OF EXCELLENCE IN CONVERGENT BIO–NANO SCIENCE AND TECHNOLOGY
Grant number: CE140100036 | Funding period: 2014 - 2021
The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an..View full description
Related publications (16)
Polyphenol-Based Nanoparticles for Intracellular Protein Delivery via Competing Supramolecular Interactions.
Yiyuan Han, Jiajing Zhou, Yingjie Hu, Zhixing Lin, Yutian Ma, Joseph J Richardson, Frank Caruso
Intracellular delivery of proteins is a promising strategy for regulating cellular behavior and therefore has attracted interest f..
Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies
Zachary H Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B Howard, Nicholas L Fletcher, Adrian V Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W Boyd, Stephen M Mahler, Linda J Richards, Frank Caruso, Kristofer J Thurecht
Increasing accumulation and retention of nanomedicines within tumor tissue is a significant challenge, particularly in the case of..
Physically-plausible modelling of biomolecular systems: A simplified, energy-based model of the mitochondrial electron transport chain
Peter J Gawthrop, Peter Cudmore, Edmund J Crampin
Advances in systems biology and whole-cell modelling demand increasingly comprehensive mathematical models of cellular biochemistr..
Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation.
Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Yi Ju, Wenbo Jiang, Verena C Wimmer, Brigette C Duckworth, Joanna R Groom, Frank Caruso, Masaru Kanekiyo, Stephen J Kent, Adam K Wheatley
Protein-based, self-assembling nanoparticles elicit superior immunity compared with soluble protein vaccines, but the immune mecha..
Link between Low-Fouling and Stealth: A Whole Blood Biomolecular Corona and Cellular Association Analysis on Nanoengineered Particles
Alessia CG Weiss, Hannah G Kelly, Matthew Faria, Quinn A Besford, Adam K Wheatley, Ching-Seng Ang, Edmund J Crampin, Frank Caruso, Stephen J Kent
Upon exposure to human blood, nanoengineered particles interact with a multitude of plasma components, resulting in the formation ..