BIO-METROLOGY AND MODELLING OF A COMPLEX SYSTEM: THE MALARIA PARASITE (UM CASH CONTRIBUTIONS)

Grant number: FL150100106 | Funding period: 2016 - 2021

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Abstract

This fellowship project aims to develop a cross-disciplinary program to measure, model and manipulate a complex cellular system — sexual differentiation of the human malaria parasite. Combining life and physical sciences with powerful imaging techniques, the project seeks to develop quantitative biochemical, biophysical and modelling techniques to probe a complex system in a way previously not possible. It expects to integrate and correlate thousands of measurements of the dynamic processes inside cells and use these datasets to generate rigorous and sophisticated mathematical models that can predict drivers of commitment for transformation of the parasite to a sexual phase in preparation fo..

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