Targeting Angiotensin Converting Enzyme 2 in Chronic Kidney Disease

Adverse cardiac effects of exogenous angiotensin 1-7 in rats with subtotal nephrectomy are prevented by ACE inhibition

LM Burrell, D Gayed, K Griggs, SK Patel, E Velkoska

2017-02-01

We previously reported that exogenous angiotensin (Ang) 1±7 has adverse cardiac effects in experimental kidney failure due to its ..

Angiotensin converting enzyme 2 and diminazene: role in cardiovascular and blood pressure regulation

E Velkoska, SK Patel, LM Burrell

2016-09-01

Purpose of review Angiotensin converting enzyme 2 (ACE2) is an important regulator of the renin-angiotensin system through actions..

Diminazene aceturate improves cardiac fibrosis and diastolic dysfunction in rats with kidney disease

E Velkoska, SK Patel, K Griggs, LM Burrell

2016-08-01

Angiotensin converting enzyme (ACE) 2 is a negative regulator of the renin angiotensin system (RAS) through its role to degrade an..