Prediction of Late Death or Disability at Age 5 Years Using a Count of 3 Neonatal Morbidities in Very Low Birth Weight Infants
Barbara Schmidt, Robin S Roberts, Peter G Davis, Lex W Doyle, Elizabeth V Asztalos, Gillian Opie, Aida Bairam, Alfonso Solimano, Shmuel Arnon, Reginald S Sauve
JOURNAL OF PEDIATRICS | MOSBY-ELSEVIER | Published : 2015
OBJECTIVE: To evaluate bronchopulmonary dysplasia (BPD), serious brain injury, and severe retinopathy of prematurity (ROP) as predictors of poor long-term outcome in very low birth weight infants. STUDY DESIGN: We examined the associations between counts of the 3 morbidities and long-term outcomes in 1514 of 1791 (85%) infants with birth weights of 500-1250 g who were enrolled in the Caffeine for Apnea of Prematurity trial from October 1999, to October 2004, had complete morbidity data, and were alive at 36 weeks postmenstrual age (PMA). BPD was defined as use of supplemental oxygen at 36 weeks PMA. Serious brain injury on cranial ultrasound included grade 3 and 4 hemorrhage, cystic perivent..View full abstract
Awarded by Canadian Institutes of Health Research
Funded by the Canadian Institutes of Health Research (MCT-13288). The authors declare no conflicts of interest.