Journal article

Analyzing systolic-diastolic interval interaction characteristics in diabetic cardiac autonomic neuropathy progression

MH Imam, CK Karmakar, HF Jelinek, M Palaniswami, AH Khandoker

IEEE Journal of Translational Engineering in Health and Medicine | Institute of Electrical and Electronics Engineers (IEEE) | Published : 2015


Cardiac autonomic neuropathy (CAN), one of the major complications in diabetes, if detected at the subclinical stage allows for effective treatment and avoiding further complication including cardiovascular pathology. Surface ECG (Electrocardiogram)-based diagnosis of CAN is useful to overcome the limitation of existing cardiovascular autonomic reflex tests traditionally used for CAN identification in clinical settings. The aim of this paper is to analyze the changes in the mechanical function of the ventricles in terms of systolic-diastolic interval interaction (SDI) from a surface ECG to assess the severity of CAN progression [no CAN, early CAN (ECAN) or subclinical CAN, and definite CAN (..

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