Journal article
White matter abnormalities and impaired attention abilities in children born very preterm
AL Murray, DK Thompson, L Pascoe, A Leemans, TE Inder, LW Doyle, JFI Anderson, PJ Anderson
Neuroimage | Published : 2016
Abstract
While attention impairments are commonly observed in very preterm (<. 32. weeks' gestational age) children, neuroanatomical correlates of these difficulties are unclear. We aimed to determine whether the microstructural organization of key white matter tracts thought to be involved in attention (cingulum bundle, superior longitudinal fasciculi, reticular activating system, and corpus callosum) were altered in very preterm children compared with term-born controls. We also aimed to determine whether alterations in microstructural organization of these tracts were associated with attention functioning in very preterm children. One hundred and forty-nine very preterm children and 36 term-born c..
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Awarded by National Institutes of Health
Funding Acknowledgements
We acknowledge the input of the VIBeS and Developmental Imaging research teams, the Melbourne Children's MRI Centre, and all the families who participated in this study. This study was funded by Australia's National Health & Medical Research Council [Project Grants (237117 & 491209), Early Career Award (1012236 to D.T.), Senior Research Fellowship (1081288 to P.A.), Centre of Research Excellence (1060733)], and National Institutes of Health (HD058056). The research of AL is supported by VIDI Grant 639.072.411 from the Netherlands Organisation for Scientific Research (NWO). We also acknowledge the indirect support provided by the Murdoch Childrens Research Institute, the Royal Children's Hospital Foundation, and the Victorian Government's Operational Infrastructure Support Program. The information in this manuscript and the manuscript itself has never been published either electronically or in print, and there are no conflicts of interest.