Conference Proceedings
The role of dopamine receptors in regulating the size of axonal arbours
DI Finkelstein, CL Parish, D Stanic, E Borrelli, J Drago, MK Horne, LFB Nicholson (ed.), RLM Faull (ed.)
BASAL GANGLIA VII | KLUWER ACADEMIC/PLENUM PUBL | Published : 2002
Abstract
Neurones in the adult central nervous system can form new synapse and branches1-3. These changes can also be seen following injury to the striatum or the Substantia Nigra pars compacta (SNpc) and include the formation of new synaptic terminals, growth-cones, neunte formation, increased number of tyrosine hydroxylase immunoreactive (TH-ir) hypertrophic fibres penetrating the striatum and the upregulated expression of factors that support neunte outgrowth and cell survival4-12.