Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9
Louisa J Phillipson, David H Segal, Tracy L Nero, Michael W Parker, Soo San Wan, Melanie de Silva, Mark A Guthridge, Andrew H Wei, Christopher J Burns
Bioorganic & Medicinal Chemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2015
Awarded by Australian National Health and Medical Research Council
This work is supported by scholarships, fellowships and grants from the Australian National Health and Medical Research Council (Research Fellowship to M.W.P.; Independent Research Institutes Infrastructure Support Scheme Grants 9000220 and 9000225), Victorian State Government Operational Infrastructure Support (OIS) Grants, Australian Cancer Research Foundation, and Dyson Bequest funding (Dunn Fellowship to C.J.B.). We thank Prof. D.C.S. Huang for helpful advice and discussion. Ms. Dana Buczek is acknowledged for analytical support.