Childhood Physical Performance Measures and Adulthood Knee Cartilage Volume and Bone Area: A 25-Year Cohort Study
Benny Antony, Graeme Jones, Alison Venn, Flavia M Cicuttini, Lyn March, Leigh Blizzard, Terence Dwyer, Marita Cross, Changhai Ding
Arthritis Care & Research | WILEY | Published : 2015
OBJECTIVE: We aimed to determine the associations between childhood physical performance measures and tibial cartilage volume and tibial bone area in adults 25 years later. METHODS: Participants (n = 330, ages 31-41 years, female 47%) were selected from the Australian Schools Health and Fitness Survey of 1985. The participants underwent T1-weighted fat-suppressed magnetic resonance imaging (MRI) of their knees. Tibial bone area and cartilage volume were measured from MRI. Childhood measures, including physical work capacity at 170 beats per minute (PWC170 ), leg strength, number of sit-ups, long-run, and short-run were measured in 1985. PWC170 and leg strength measures were repeated after 20..View full abstract
Supported by the National Health and Medical Research Council of Australia. Dr. Jones's work was supported by a National Health and Medical Research Council Practitioner Fellowship. Dr. Venn's work was supported by a National Health and Medical Research Council Senior Research Fellowship. Dr. Blizzard's work was supported by a National Health and Medical Research Council Career Development Fellowship. Dr. Ding's work was supported by an Australian Research Council Future Fellowship.Dr. March has received speaking fees (less than0,000) from Sevier Australia and has provided expert testimony for Sevier Australia.