Journal article
A New MRI-Based Pediatric Subcortical Segmentation Technique (PSST)
WY Loh, A Connelly, JLY Cheong, AJ Spittle, J Chen, C Adamson, ZM Ahmadzai, LG Fam, S Rees, KJ Lee, LW Doyle, PJ Anderson, DK Thompson
Neuroinformatics | Published : 2016
Abstract
Volumetric and morphometric neuroimaging studies of the basal ganglia and thalamus in pediatric populations have utilized existing automated segmentation tools including FIRST (Functional Magnetic Resonance Imaging of the Brain’s Integrated Registration and Segmentation Tool) and FreeSurfer. These segmentation packages, however, are mostly based on adult training data. Given that there are marked differences between the pediatric and adult brain, it is likely an age-specific segmentation technique will produce more accurate segmentation results. In this study, we describe a new automated segmentation technique for analysis of 7-year-old basal ganglia and thalamus, called Pediatric Subcortica..
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Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development
Funding Acknowledgements
This study was supported by Australia's National Health & Medical Research Council (Centre for Clinical Research Excellence 546519 to L. D. and P. A.; Centre for Research Excellence 1060733 to L. D., P. A., J. C., D. T., A. S., and W. Y. L.; Project Grants 237117 to L. D., 491209 to P. A.; Senior Research Fellowship 628371 to P. A., Early Career Fellowships 1053767 to A. S., 1012236 to D. T., 1053787 to J. C., National Institutes of Health (HD058056), the Victorian Government's Operational Infrastructure Support Program, and The Royal Children's Hospital Foundation.