Early endometrial microvascular response during implantation in the rat

Abstract

The endometrial microvasculature becomes intimately involved in the events of early implantation. This paper reviews aspects of this microvascular involvement during implantation in the rat. There isa major increase in vascular permeability surrounding the implanting embryo, leading to significantlocal changes in microvascular architecture. This is followed by a shutdown of the capillaries closestto the embryo as the primary decidual zone develops. At this time, endometrial capillaries adjacent tothe primary decidual zone become dilated, with over twice the average diameter of intersite capillaries.Endometrial neutrophils are reduced around the implanting blastocyst, mitigating against a rol..