Morphometric and freeze fracture studies of human endometrium duringthe peri-implantation period

Abstract

This paper reviews recent morphological work on peri-implantation endometrium collected from the Monash University In vitro FertilizationjJVF) Programme. Comparisons of endometrial tissue collectedfrom women who had undergone different superovulation regimens demonstrated that significantstructural differences could be detected by morphometry and ultrasound, but not by routine histo-pathology. Morphometric studies on endometrium from agonadal women receiving hormone replacementtherapy demonstrated major differences between women with identical endocrine profiles. A biopsyinadvertently taken from one of these patients at the time of implantation was not of the appearanceclassically believed t..