Cervical adenoid basal carcinoma, five cases and literature review

Abstract

Adenoid basal carcinoma (ABC) is a rarely reported type of invasive cervical carcinoma with distinct clinical and pathological features. To make clinicians and pathologists more aware of this tumor and to investigate its pathogenesis, five new cases with human papillomavirus (HPV) DNA studies and a literature review of 30 cases were presented. The following tendencies of ABC were confirmed: occurrence in an older age group, absence of symptoms, abnormal Papanicolaou (Pap) smear, normal pelvic examination, endophytic growth pattern, associated cervical intra-epithelial neoplasia, low nuclear grade, absence of vascular space invasion, absence of nodal metastases, low stage and good prognosis. ..