Lung function in adult survivors of very low birth weight, with and without bronchopulmonary dysplasia

Abstract

Summary Introduction The lung function outcome of cohorts of very low birth weight (VLBW; birth weight 2499 g), and in those who had bronchopulmonary dysplasia (BPD) compared with those without BPD. Materials and Methods Spirometry and lung volumes were measured according to standard guidelines when subjects were in their mid-20s; there were 47 survivors of birth weight 2499 g. Results were converted to z-scores. Results Both subgroups with birth weight <1501 g had significant reductions in airflow compared with controls, but not compared with each other. There were no significant differences between groups in variables reflecting air trapping. Within the VLBW cohort, those with BPD (n = 24)..