G-CSF Mobilised Progenitor Cells in Autologous Transplantation: In vitro and in vivo aspects

Abstract

G-CSF administration leads to significant elevation in the levels of circulating progenitor cells. Infusion of these cells after high-dose chemotherapy is associated with accelerated platelet engraftment that has a considerable impact in shortening thrombocytopenia and reducing need for platelet transfusions. © 1992, Center for Academic Publications Japan. All rights reserved.