Journal article

Variability in determination of body weight used for dosing busulphan and cyclophosphamide in adult patients: Results of an international survey

A Grigg, MH Harun, J Szer

LEUKEMIA & LYMPHOMA | HARWOOD ACAD PUBL GMBH | Published : 1997

Abstract

Fifty-two BMT institutions were sent a questionnaire asking for details of dosing for busulphan, cyclophosphamide (bu-cy), cyclosporin and methotrexate (CSA-MTX). The following data were requested: (a) the method used to determine the body weight for dosage calculations (b) the actual dose per weight and (c) the schedule of administration. Thirty-six (69%) institutions responded and 33 were evaluable. There was substantial variation in the method used to determine weight for bu-cy. No single method was used in more than 30% of units, although most units made some allowance for discrepancies between actual and ideal body weight. There was more uniformity in the method of weight determination ..

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