ASPIRIN AND PREVENTION OF PREECLAMPSIA

Abstract

Summary: 1. A heterogeneous group of randomized trials have been conducted using low‐dose aspirin to prevent preeclampsia. The results do not support widespread use of low‐dose aspirin to prevent preeclampsia.2. On the basis of existing literature, it is reasonable to use prophylactic low‐dose aspirin from early pregnancy in the following groups:(i) Women with prior fetal loss after the first trimester, with placental insufficiency (ii) Women with severe fetal growth retardation in a preceding pregnancy eitherdue to preeclampsia or unexplained(iii) Women with severe early‐onset preeclampsia in a previous pregnancynecessitating delivery at or before 32 weeks' gestation.3. On the basis of exi..