Journal article

COMPARISONS BETWEEN THE ABILITIES OF VARIOUS HUMAN AND OVINE PLASMAS TO INHIBIT PROSTAGLANDIN SYNTHESIS

MD MITCHELL, SP BRENNECKE, PA DENNINGKENDALL, WJM GIBSON, SA SAEED, HOJ COLLIER

Prostaglandins and Medicine | LONGMAN GROUP UK LTD | Published : 1981

Abstract

The ability of various human and ovine blood plasmas to inhibit prostaglandin synthesis in vitro has been tested. Human plasmas were significantly more potent in their ability to inhibit prostaglandin synthesis than their counterpart ovine plasmas. In general, female plasma had greater inhibitory activities than male plasmas and adult plasmas were more active than fetal plasmas. There was no simple correlation between the activity of plasmas as inhibitors of prostaglandin synthesis and their respective albumin or haptoglobin contents.