Journal article

HLA-G DELETION POLYMORPHISM AND PREECLAMPSIA ECLAMPSIA

KE HUMPHREY, GA HARRISON, DW COOPER, AN WILTON, SP BRENNECKE, BJ TRUDINGER

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | BLACKWELL SCIENCE LTD | Published : 1995

Abstract

OBJECTIVE: To investigate a HLA-G deletion polymorphism in pre-eclamptic pedigrees and the general population. DESIGN: A population association study of HLA-G genotypes from pre-eclamptic/eclamptic patients and control groups. SETTING: Analyses undertaken in the School of Biological Sciences, Macquarie University. Patients were from Royal Women's Hospital, Melbourne, and controls were from Westmead Hospital and Macquarie University, Sydney. SUBJECTS: One hundred and ninety-six individuals, consisting of 29 pre-eclamptic/eclamptic (PE/E) patients, 13 individuals born of a PE/E pregnancy, 46 blood relatives of PE/E patients, 21 husbands of PE/E patients, 25 women normotensive in first pregnanc..

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