Journal article

CHANGES IN BONE-MINERAL DENSITY OF THE PROXIMAL FEMUR AND SPINE WITH AGING - DIFFERENCES BETWEEN THE POST-MENOPAUSAL AND SENILE OSTEOPOROSIS SYNDROMES

BL RIGGS, HW WAHNER, E SEEMAN, KP OFFORD, WL DUNN, RB MAZESS, KA JOHNSON, LJ MELTON

Journal of Clinical Investigation | AMER SOC CLINICAL INVESTIGATION INC | Published : 1982

Abstract

We measured bone mineral density (BMD) of the proximal femur, lumbar spine, or both by dual photon absorptiometry in 205 normal volunteers (123 women and 82 men; age range 20 to 92 yr) and in 31 patients with hip fractures (26 women and 5 men; mean age, 78 yr). For normal women, the regression of BMD on age was negative and linear at each site; overall decrease during life was 58% in the femoral neck, 53% in the intertrochanteric region of the femur, and 42% in the lumbar spine. For normal men, the age regression was linear also; the rate of decrease in BMD was two-thirds of that in women for femoral neck and intertrochanteric femur but was only one-fourth of that in women for lumbar spine. ..

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University of Melbourne Researchers