Changes in triglyceride levels in ultra-high risk for psychosis individuals treated with omega-3 fatty acids
Nilufar Mossaheb, Konstantinos Papageorgiou, Miriam R Schaefer, Jana Becker, Monika Schloegelhofer, G Paul Amminger
Early Intervention in Psychiatry | WILEY | Published : 2018
AIM: The aim of this analysis was to assess changes in lipid parameters, specifically in triglyceride (TG) levels, in a population at ultra-high risk (UHR) for psychosis treated with ω-3 polyunsaturated fatty acids (PUFAs) versus placebo. METHODS: Data were derived from a randomized, double-blind, placebo-controlled trial conducted at an early psychosis unit. Eighty-one individuals, aged 13-25 years, at UHR for psychosis participated in a 12-week intervention trial of 1.2 g/day of ω-3 PUFAs (n = 41) versus placebo (n = 40). Lipid and C-reactive protein levels were collected at baseline and after 12 weeks. RESULTS: Between-group comparisons showed no significant difference in TG levels after ..View full abstract
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Awarded by Stanley Medical Research Institute
The study was supported by grant 03T-315 from the Stanley Medical Research Institute.