Anesthetic depth and long-term survival: an update

Abstract

PURPOSE: The purpose of this paper is to review the current evidence relating anesthetic depth to long-term survival after surgery. SOURCE: Using PubMed as the principal source, this review included published studies in all languages comparing mortality in patients with low- and high-processed electro-encephalo-graphic index values. PRINCIPAL FINDINGS: All published studies used the bispectral index (BIS) monitor to measure anesthetic depth. The majority of the published observational studies were post hoc analyses of studies undertaken for other purposes. Most of these studies report a statistically significant association between deep general anesthesia (i.e., BIS values 80 group, and two..