Journal article

Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes

Colm PF O'Donnell, Matteo Bruschettini, Peter G Davis, Colin J Morley, Lorenzo Moja, Maria Grazia Calevo, Simona Zappettini

Cochrane Database of Systematic Reviews | WILEY-BLACKWELL | Published : 2015

Abstract

BACKGROUND: At birth, infants' lungs are fluid-filled; this fluid must be replaced by air to allow for effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volume in the lungs. OBJECTIVES: To assess the efficacy of initial sustained (> one second duration) lung inflation compared to standard inflations (≤ one second) in newly born infants receiving resuscitation with intermittent PPV. SEARCH METHODS: We searched on PubMed (1966 to 1 February 2015), EMBASE (1980 to 1 February 2015) and the Cochrane ..

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Grants

Awarded by Federal funds from Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA


Funding Acknowledgements

Institute for Clinical Sciences, Lund University, Lund, Sweden.Royal Women's Hospital, Melbourne, Australia.University of Melbourne, Australia.Istituto Giannina Gaslini, Genoa, Italy.Murdoch Childrens Research Insitute, Australia.National Health and Medical Research Council, Australia.Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA.Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN275201100016C.