Journal article

Multimerization of a Proline-Rich Antimicrobial Peptide, Chex-Arg20, Alters Its Mechanism of Interaction with the Escherichia coli Membrane

Wenyi Li, Neil M O'Brien-Simpson, Julien Tailhades, Namfon Pantarat, Raymond M Dawson, Laszlo Otvos, Eric C Reynolds, Frances Separovic, Mohammed Akhter Hossain, John D Wade

Chemistry & Biology | CELL PRESS | Published : 2015


Awarded by ARC Discovery Project

Awarded by NHMRC Project

Funding Acknowledgements

Super-resolution imaging was performed at the Materials Characterization and Fabrication Platform (MCFP) at the University of Melbourne. We thank Shu Lam and Greg Qiao (Chemical and Biomolecular Engineering, University of Melbourne) for assistance with application of their high-resolution fluorescent microscopy technique to our studies. We gratefully acknowledge support of the studies undertaken in the authors' laboratory by an ARC Discovery Project grant (DP150103522) to J.D.W. and M.A.H., and NHMRC Project grants (APP1029878) to N.M.O'B.S. and (APP1008106) to E.C.R. and N.M.O'B.S. J.D.W. is an NHMRC (Australia) Principal Research Fellow. W.L. is the recipient of an MIRS PhD award. Research at the FNI was also supported by the Victorian Government's Operational Infrastructure Support Program.