Journal article

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

Neil M Davies, Tom R Gaunt, Sarah J Lewis, Jeff Holly, Jenny L Donovan, Freddie C Hamdy, John P Kemp, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis Show all

Cancer Causes & Control | SPRINGER | Published : 2015

Grants

Awarded by World Cancer Research Fund


Awarded by Cancer Research UK


Awarded by European Commission's Seventh Framework Programme


Awarded by National Institute of Health (NIH) Cancer Post-Cancer GWAS initiative


Awarded by UK Health Technology Assessment (HTA) Programme of the NIH Research


Awarded by Medical Research Council and Cancer Research UK


Awarded by University of Bristol


Awarded by Medical Research Council


Awarded by National Institute for Health Research


Funding Acknowledgements

Support for the analysis was provided by the World Cancer Research Fund (2011/419) and Cancer Research UK (C18281/A19169). The CRUK study and the PRACTICAL consortium were supported by the Canadian Institutes of Health Research; the European Commission's Seventh Framework Programme Grant agreement number 223175 (HEALTH-F2-2009-223175); Cancer Research UK Grants C5047/A7357, C1287/A10118, C5047/A3354, C5047/A10692, C16913/A6135; and the National Institute of Health (NIH) Cancer Post-Cancer GWAS initiative Grant No. 1 U19 CA 148537-01 (the GAME-ON initiative). The ProtecT study is funded by the UK Health Technology Assessment (HTA) Programme of the NIH Research (HTA 96/20/99; ISRCTN20141297). The authors thank the provision of the additional epidemiological data by the NHS R&D Directorate supported Prodigal study and the ProMPT (Prostate Mechanisms of Progression and Treatment) collaboration which is supported by the National Cancer Research Institute (NCRI) formed by the Department of Health, the Medical Research Council and Cancer Research UK (G0500966/75466). RAE and ZKJ are supported by Cancer Research UK Grant C5047/A7357 and the NIHR Biomedical Research Centre at The Institute of Cancer Research and Royal Marsden NHS Foundation Trust. RMM was supported by the National Institute for Health Research Bristol Nutrition Biomedical Research Unit based at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. FCH, DEN and JLD are NIHR Senior Investigators. The Integrative Epidemiology Unit is supported by the MRC and the University of Bristol (G0600705, MC_UU_12013/1,9). No funding body has influenced data collection, analysis, or its interpretations. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. This publication is the work of the authors, who serve as the guarantors for the contents of this paper.