Journal article
Neuroanatomical Assessment of Biological Maturity
Timothy T Brown, Joshua M Kuperman, Yoonho Chung, Matthew Erhart, Connor McCabe, Donald J Hagler, Vijay K Venkatraman, Natacha Akshoomoff, David G Amaral, Cinnamon S Bloss, BJ Casey, Linda Chang, Thomas M Ernst, Jean A Frazier, Jeffrey R Gruen, Walter E Kaufmann, Tal Kenet, David N Kennedy, Sarah S Murray, Elizabeth R Sowell Show all
CURRENT BIOLOGY | CELL PRESS | Published : 2012
Abstract
Structural MRI allows unparalleled in vivo study of the anatomy of the developing human brain. For more than two decades, MRI research has revealed many new aspects of this multifaceted maturation process, significantly augmenting scientific knowledge gathered from postmortem studies. Postnatal brain development is notably protracted and involves considerable changes in cerebral cortical, subcortical, and cerebellar structures, as well as significant architectural changes in white matter fiber tracts (see [12]). Although much work has described isolated features of neuroanatomical development, it remains a critical challenge to characterize the multidimensional nature of brain anatomy, captu..
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Awarded by PING (National Institutes of Health)
Awarded by EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH
Awarded by NATIONAL INSTITUTE ON DRUG ABUSE
Funding Acknowledgements
The authors gratefully thank the children, adolescents, adults, and parents who participated in the research. Data used in preparation of this study were obtained from the Pediatric Imaging, Neurocognition, and Genetics Study (PING) database. As such, the investigators within PING contributed to the design and implementation of PING and/or provided data but did not necessarily participate in the analysis or writing of this report. A complete listing of PING investigators can be found at http://ping.chd.ucsd.edu. Data collection and sharing for this project was funded by PING (National Institutes of Health grant RC2DA029475), which is funded by the National Institute on Drug Abuse and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. PING data are disseminated by the PING Coordinating Center at the Center for Human Development, University of California, San Diego. A.M.D. is a founder & and holds equity interest in CorTechs Labs, La Jolla, CA, and serves on its scientific advisory board. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies.