EXPRESSION OF TENASCIN IN PERIFOLLICULAR CONNECTIVE-TISSUE - COMPARISON OF NORMAL SCALP AND ALOPECIA-AREATA
HMJ VANBAAR, CM PERRET, IMJJ VANVLIJMENWILLEMS, JPM CLEUTJENS, EJ MACKIE, R HAPPLE, J SCHALKWIJK
Archives of Dermatological Research | SPRINGER | Published : 1991
Tenascin, a recently discovered extracellular matrix protein, was demonstrated in perifollicular connective tissue of normal human scalp using immunohistochemistry. Its localization was different from other well-known extracellular matrix components, like fibronectin, laminin and heparan sulphate proteoglycan. A comparison between alopecia areata and normal scalps did not reveal major qualitative differences, except for an increased expression near heavily infiltrated follicles.