Prophylactic antibiotics for inhibiting preterm labour with intact membranes.
Vicki Flenady, Glenda Hawley, Owen M Stock, Sara Kenyon, Nadia Badawi
Cochrane Database Syst Rev | Published : 2013
BACKGROUND: The aetiology of preterm birth is complex and there is evidence that subclinical genital tract infection influences preterm labour in some women but the role of prophylactic antibiotic treatment in the management of preterm labour is controversial. Since rupture of the membranes is an important factor in the progression of preterm labour, it is important to see if the routine administration of antibiotics confers any benefit or causes harm, prior to membrane rupture. OBJECTIVES: To assess the effects of prophylactic antibiotics administered to women in preterm labour with intact membranes, on maternal and neonatal outcomes. SEARCH METHODS: We searched the Cochrane Pregnancy and C..View full abstract