Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression

Abstract

The gene nmrA of Aspergilus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in nitrogen metabolite repression. Deletion of nmrA results in partial derepression of activities subject to nitrogen repression similar to phenotypes observed for certain mutations in the positively acting areA gene.