Journal article

INITIATION OF DEVELOPMENT OF DIAPAUSING EMBRYO BY MAMMARY DENERVATION DURING LACTATION IN A MARSUPIAL

MB RENFREE

NATURE | MACMILLAN MAGAZINES LTD | Published : 1979

Abstract

MOST macropodid marsupials conceive at postpartum oestrus and the 100-cell embryo enters into and remains in embryonic diapause while there is a suckling young in the pouch1. Removal of the pouch young results in reactivation of the quiescent corpus luteum and of the diapausing blastocyst. Prolactin inhibits corpus luteum development tonically during lactational quiescence in the tammar wallaby, Macropus eugenii2. However, it is not known whether the hormonal milieu associated with lactation, or the neural stimulus of suckling itself is the primary signal to the hypothalamus which results in the maintenance of embryonic diapause in M. eugenii. I therefore examined the role of the neural path..

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University of Melbourne Researchers