The uterine environment in early pregnancy in the tammar wallaby.
Reprod Fertil Dev | Published : 1996
In tammar wallabies, Macropus eugenii, the uterine environment plays a key role in regulating development, because during the first two-thirds of gestation an acellular mucoid coat and shell prevent direct cell-cell contact between the endometrium and embryonic cells. This control is seen very clearly in the facultative lactational diapause of tammars. Removal of the suckled pouch young during the breeding season terminates diapause, leading to a distinct increase in metabolic activity of the embryo. By Day 4, oxidative metabolism of glucose has substantially increased, providing a four-fold increase in ATP production. By Day 5, RNA synthesis has increased. These changes are dependent on pro..View full abstract