Journal article

Multiparametric 3T MRI in the evaluation of intraglandular prostate cancer: Correlation with histopathology

Colin Styles, Nicholas Ferris, Catherine Mitchell, Declan Murphy, Mark Frydenberg, John Mills, John Pedersen, Noelene Bergen, Gillian Duchesne

Journal of Medical Imaging and Radiation Oncology | WILEY | Published : 2014

Abstract

INTRODUCTION: Prostate cancer is common and may be treated immediately or managed conservatively by observation. We sought to determine how reliable multiparametric MRI is in the detection of intraprostatic prostate cancer and what role it has in risk stratification. METHODS: The histology from 38 whole mount prostate specimens was compared with preoperative multiparametric 3T MRI studies with an endorectal receiver coil in place. T1-weighted, T2-weighted, diffusion (b values 50 400 800), perfusion (Ve , Kep , Ktrans , area under the curve) and proton spectroscopic sequences were used. RESULTS: For cancers greater than 0.5 cc, the detection rate for combined T2-weighted imaging and diffusion..

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