Journal article

Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica

Andrew J Gentles, Matthew J Wakefield, Oleksiy Kohany, Wanjun Gu, Mark A Batzer, David D Pollock, Jerzy Jurka

Genome Research | COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT | Published : 2007

Abstract

The genome of the gray short-tailed opossum Monodelphis domestica is notable for its large size ( approximately 3.6 Gb). We characterized nearly 500 families of interspersed repeats from the Monodelphis. They cover approximately 52% of the genome, higher than in any other amniotic lineage studied to date, and may account for the unusually large genome size. In comparison to other mammals, Monodelphis is significantly rich in non-LTR retrotransposons from the LINE-1, CR1, and RTE families, with >29% of the genome sequence comprised of copies of these elements. Monodelphis has at least four families of RTE, and we report support for horizontal transfer of this non-LTR retrotransposon. In addit..

View full abstract