Journal article

SWALLOWING OF LUNG LIQUID AND AMNIOTIC-FLUID BY THE OVINE FETUS UNDER NORMOXIC AND HYPOXIC CONDITIONS

RA BRACE, ME WLODEK, ML COCK, R HARDING

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | MOSBY-YEAR BOOK INC | Published : 1994

Abstract

OBJECTIVE: The lungs of the mammalian fetus secrete large volumes of fluid daily. The purpose of this study was to estimate the fraction of the lung liquid that is swallowed as it exits the fetal trachea versus that which enters the amniotic fluid under normoxic and hypoxic conditions. STUDY DESIGN: In chronically catheterized fetal sheep at 119 to 133 days' gestation the volume of fluid swallowed by the fetus was monitored five times per day for three consecutive 24-hour periods: control, hypoxia, and recovery. The Na+, K+, and Cl- concentrations of the swallowed fluid, lung liquid, and amniotic fluid were measured simultaneously. The fraction of the swallowed fluid that originated from the..

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