Guidelines for the surveillance and management of familial adenomatous polyposis (FAP): A world wide survey among 41 registries

Abstract

Objective FAP is an autosomal dominant disease characterized by numerous adenomas in the colorectum. The majority of patients also develop adenomas in the duodenum. The purpose of the study was to evaluate the management and screening protocols implemented in FAP families at various polyposis registries in the world. Methods A questionnaire was mailed to the members of The Leeds Castle Polyposis Group requesting information on: diagnostic evaluation of polyposis, recommendations for screening and surgical management of the colon, surveillance of the upper gastrointestinal tract and the management of duodenal polyposis. Results Almost all members agreed that a newly diagnosed patient should b..