Systematic noise degrades gene co-expression signals but can be corrected

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Funding Acknowledgements

We acknowledge Karen Oliver and Vesna Lukic for providing lists of known eplileptic encephalopathy genes and candidates. Furthermore, we would like to thank Matthew Ritchie for helpful discussions on preprocessing of gene expression data and Peter Hickey with programing advice. This work was funded in part by Australian National Health and Medical Research Council (NHMRC) program grant 490037. MB was supported by an Australian Research Council Future Fellowship (FT100100764). We also want to thank Michael Hawrylycz and Changkyu Lee at the Allen Institute of Brain Science for their patience in answering our many questions concerning the Miller et al. data.